Research
Neutrophil-to-Lymphocyte, Lymphocyte-to-Monocyte, and Platelet-to-Lymphocyte Ratios: Prognostic Significance in COVID-19
This study aimed at examining the prognostic value of normal and derived neutrophil-to-lymphocyte, lymphocyte-to-monocyte, platelet-to-lymphocyte, and mean platelet volume (MPV)-to-platelet count ratios in patients with coronavirus disease 2019 (COVID-19).
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Prognosis of COVID-19: Red Cell Distribution Width, Platelet Distribution Width, and C-Reactive Protein
Red cell distribution width, platelet distribution width, and C-reactive protein are useful early predictive markers of mortality in COVID-19.
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Artificial intelligence in clinical medicine: catalyzing a sustainable global healthcare paradigm
Artificial intelligence in clinical medicine: catalyzing a sustainable global healthcare paradigm
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Factors Contributing Towards Poor Asthma Control in Patients on Regular Medication
There is a need for an objective monitoring in asthma and the treatment strategies need to be modified accordingly.
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Liver: Function and dysfunction in COVID-19
COVID-19 is known to cause extrapulmonary manifestations, including gastrointestinal and abnormal liver functions. Multiple mechanisms have been proposed to explain the pathobiology of liver damage: ACE2 receptor cholangiocytes mediated systemic inflammation, cytokine storm, hyperinflammation, and hypoxic changes.
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Allopurinol: Sorrow to the marrow
we here report a case of allopurinol induced aplastic anemia leading to the demise of a patient. Allopurinol though safe needs careful monitoring.
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A Case of Disseminated Melioidosis With Cerebritis
Melioidosis is caused by Burkholderia pseudomallei, a Gram-negative, facultative intracellular bacterium. Because melioidosis can mimic many diseases, it requires more advanced laboratory facilities with the necessary expertise and can become an underdiagnosed yet serious infection with high mortality and morbidity
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Aspirin vs Clopidogrel: Antiplatelet Agent of Choice for Those With Recent Bleeding or at Risk for Gastrointestinal Bleed
Antiplatelet agents are used worldwide mainly for primary and secondary prevention of cardiovascular events on a long-term basis for mortality benefit. Gastrointestinal bleeding is a well-known adverse effect.
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Hiccups and hyponatremia: Unusual co-presentation in COVID-19
This extremely rare case report brings to light new atypical symptom of COVID-19 are being presented every other day, which shows how the importance being aware of the same.
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Hemophagocytic Lymphohistiocytosis: A Scourge for the Physician and Bane to the Bone Marrow
Hemophagocytic lymphohistiocytosis (HLH) is a condition characterized by hyperinflammation. It can occur due to primary genetic defect or secondary to other etiology such as infection and rheumatological conditions.
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Dengue Fever: Prognostic Insights From a Complete Blood Count
Dengue fever is endemic in more than 100 countries. Early indicators of prognosis are vital to reduce the fatality rate associated with dengue fever. The objective of this study is to investigate the value of a complete blood count (CBC) in determining the prognosis of dengue fever.
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Relationship between Nighttime BP and Urine Microalbumin to Creatinine Ratio
Relationship between Nighttime BP and Urine Microalbumin to Creatinine Ratio
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Insulin, Insulin Everywhere: A Rare Case Report of Rabson-Mendenhall Syndrome
Rabson-Mendenhall syndrome (RMS) is a rare autosomal recessive disorder characterized by severe insulin resistance, a condition in which the body's tissues and organs do not respond appropriately to the hormone insulin. Insulin resistance impairs blood sugar regulation and ultimately leads to diabetes mellitus.
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Hepatitis A: A refreshing perspective through a rare symptom in a teaching hospital in south India
Hepatitis A virus is a common cause of acute viral hepatitis in India, due to lack of clean water and sanitation. Usual presentations include gastroenteritis or a viral respiratory infection.
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A Review of Monkeypox: Present-day Scenario in India
Monkeypox is an Orthopoxvirus whose outbreak has been noted in various parts of the world in 2022. A significant outbreak has not yet occurred in India and various other developing countries.
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What Haemodialysis Does to QTC in Patients with Newly Diagnosed Chronic Kidney Disease?
What Haemodialysis Does to QTC in Patients with Newly Diagnosed Chronic Kidney Disease?
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Study on the Relation between Colorectal Cancer and Gall Bladder Disease
Colorectal cancer is cancer of the large intestine, the lower part of digestive system which includes the sigmoid colon and rectum.
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A Study of Prescription Pattern of Neutraceuticals, Knowledge of the Patients and Cost in a Tertiary Care Hospital
Neutraceuticals are increasingly becoming a part of diet in a health-conscious society. People have changed their outlook towards neutraceuticals because of varying lifestyle diseases and they see the need to improve their physical and mental health.
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Evaluation of the Role of HBA1c in Chronic kidney Disease
evaluate the role of glycated haemoglobin (HBA1c) due to type II diabetes mellitus by correlating glycated haemoglobin with estimated Glomerular Filtration Rate (GFR) and serum creatinine parameters.
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Atypical Manifestation of Dengue Fever: A Tale of 2 Cases
Dengue virus is a RNA virus belonging to flavivirus genus. Rapid raise in urban population and poor public health infrastructures have led to significant increase in the number of dengue cases.
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Relationship of Acute ST-Elevation Myocardial Infarction with hs-CRP and Serum Iron Profile in Southern India: A Cross-sectional Study
Cardiovascular diseases are a major cause of mortality. The role of Iron in oxidative myocardial damage remains controversial with multiple studies showing positive and negative correlations.
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Primary Sjogren’s Syndrome Manifesting as Recurrent Hypokalemia with Distal Renal Tubular Acidosis
Sjogren’s syndrome is an autoimmune disease with both glandular and extraglandular manifestations. We report a rare case of primary Sjogren syndrome without sicca symptoms presenting with renal tubular acidosis and recurrent hypokalaemia.
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Post Transfusion Purpura -Red Alert to Clinician
Incidence of Post Transfusion Purpura (PTP) varies between 1 : 50000 to 1 : 100000. It is a dreaded complication and needs prompt and early intervention with high degree of clinical suspicion in the absence of serological testing to decrease mortality. It is a rare severe complication occurring after blood transfusion
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Helicobacter pylori-Associated Immune Thrombocytopenia: Diagnostic and Therapeutic Approach
The relationship between immune thrombocytopenia (ITP) and Helicobacterpylori infection has largely been an unexplored entity. This review article aims at focusing on the role of H. pylori in secondary ITP.
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Bernard-Soulier Syndrome with Unusual Presentation of Splenic Infarct
Atypical presentation of Bernard-Soulier syndrome should be considered at the level of primary care itself and ultrasound of abdomen pelvis, bleeding time, clotting time and coagulation profile should be done for every 2 months as a routine workup for all bleeding disorders.
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How Does APRI Hold Up in Predicting Adverse Outcomes and Prognosis among Patients with Chronic Liver Disease?
A study on how Aspartate Aminotransferase-to-Platelet Ratio Index (APRI) Hold Up in Predicting Adverse Outcomes and Prognosis among Patients with Chronic Liver Disease Compared to Other Liver Scoring Systems.
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Spectrum and Correlation of Clinical, Radiological and Biochemical Parameters in Tuberculosis in a Hospital in South India
The objectives of the study were to describe various comorbidities in patients with tuberculosis, determine expected radiological presentations in these patients and to determine prognosis altering metabolic indicators in patients with TB
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Organophosphorus poisoning-focus on management aspects
This study examines the effects of Organophosphorus (OP) compounds, commonly used in insecticides, herbicides and industrial chemicals, on human health, highlighting exposure routes and treatment protocols.
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Current Status of Sulphonylureas after CAROLINA and CARMELINA Trial - Maximum Glycemic Efficacy with Cardiac Safety
This study reviews Sulfonylureas (SUs), cost-effective antidiabetic medications, focusing on their therapeutic effects, classification and evolution from first-generation drugs (e.g., Tolbutamide) to safer second-generation alternatives (e.g., Gliclazide, Glipizide).
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